{"id":82798,"date":"2021-09-15T12:10:51","date_gmt":"2021-09-15T07:40:51","guid":{"rendered":"https:\/\/aprinpharmed.com\/dota-toc-acetate\/"},"modified":"2023-02-09T09:02:12","modified_gmt":"2023-02-09T05:32:12","slug":"dota-toc-acetate","status":"publish","type":"page","link":"https:\/\/aprinpharmed.com\/en\/dota-toc-acetate\/","title":{"rendered":"DOTA-TOC"},"content":{"rendered":"

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Aprin Pharmed<\/div>
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DOTA-TOC<\/span><\/p>\n

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DOTA-TOC, also known as Edotreotide, is a useful compound for making radiopharmaceuticals used in imaging procedures as PET-CT Scan. In DOTA-TOC structure, the phenylalanine has been substituted for tyrosine at position 3 of the octreotide acetates, moreover, the DOTA chelator is attached to allow for the binding of various radioisotopes. DOTA-TOC, like octreotide acetate, binds to the somatostatin receptors found on the cell membranes of a variety of neurologic and glandular tumors and when labeled with radioisotopes, can lead to cytotoxicity in a specific tissue.<\/p>\n

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<\/div>[\/vc_column][\/vc_row][vc_row][vc_column width=”1\/6″][\/vc_column][vc_column width=”2\/3″]
CAS registration number<\/div><\/span>
  • <\/i><\/div>
    204318-14-9<\/span><\/div><\/li><\/ul><\/div><\/div>
    molecular mass<\/div><\/span>
    • <\/i><\/div>
      1421.6 g\/mol<\/span><\/div><\/li><\/ul><\/div><\/div>
      Molecular formula<\/div><\/span>
      • <\/i><\/div>
        C65H92N14O18S2<\/span><\/div><\/li><\/ul><\/div><\/div>
        Appearance<\/div><\/span>
        • <\/i><\/div>
          white powder<\/span><\/div><\/li><\/ul><\/div><\/div>
          synonym<\/div><\/span>
          • <\/i><\/div>
            DOTA-TOC acetate; DOTA-[Tyr3]-octreotide; Edotreotide<\/span><\/div><\/li><\/ul><\/div><\/div>
            Peptide sequence<\/div><\/span>
            • <\/i><\/div>
              This is list item<\/span><\/div><\/li><\/ul><\/div><\/div>
              Maintenance<\/div><\/span>
              • <\/i><\/div>
                20- \u062f\u0631\u062c\u0647 \u0633\u0627\u0646\u062a\u06cc\u06af\u0631\u0627\u062f<\/span><\/div><\/li><\/ul><\/div><\/div>
                Therapeutic applications<\/div><\/span>
                • <\/i><\/div>
                  Positron Emission Tomography (PET) imaging or radionuclide therapy<\/span><\/div><\/li><\/ul><\/div><\/div><\/div><\/div>[\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

                  [vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/6″][\/vc_column][vc_column width=”2\/3″][\/vc_column][vc_column width=”1\/6″][\/vc_column][\/vc_row] … <\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-82798","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/pages\/82798","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/comments?post=82798"}],"version-history":[{"count":10,"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/pages\/82798\/revisions"}],"predecessor-version":[{"id":83264,"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/pages\/82798\/revisions\/83264"}],"wp:attachment":[{"href":"https:\/\/aprinpharmed.com\/en\/wp-json\/wp\/v2\/media?parent=82798"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}